Nitrofurazone-13C,15N2

Names

[ CAS No. ]:
1217220-85-3

[ Name ]:
Nitrofurazone-13C,15N2

[Synonym ]:
Coxistat-13C,15N2
Aldomycin-13C,15N2
Nitrofurazone-13C,15N2
Alfucin-13C,15N2
(5-Nitro-2-furfurylidenamino)urea-13C,15N2
Chemofuran-13C,15N2
Babrocid-13C,15N2
Furesol-13C,15N2
Mammex-13C,15N2
Amifur-13C,15N2

Biological Activity

[Description]:

Nitrofurazone-13C,15N2 (Nitrofural-13C,15N2) is the 13C and 15N labled Nitrofurazone (HY-B0226)[1]. Nitrofurazone is a potential antibiotic that can be used topically to treat wounds, burns, ulcers and skin infections to combat various microorganisms and to prepare surfactants[1]. Nitrofurazone may affect the ecosystem function in Marine environment and affect the functional processes of epiphytic fauna[2][3].

[Related Catalog]:

Research Areas >> Infection

[In Vitro]

氢、碳和其他元素的稳定重同位素已被纳入药物分子中,主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注,因为它可能影响药物的药代动力学和代谢谱[1]。

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Uroosa, et al. Effects of nitrofurazone on ecosystem function in marine environments: A case study on microbial fauna. Mar Pollut Bull. 2022 Nov;184:114216.  

Chemical & Physical Properties

[ Molecular Formula ]:
C513CH6N215N2O4

[ Molecular Weight ]:
201.12

[ Exact Mass ]:
201.03600

[ PSA ]:
127.43000

[ LogP ]:
1.61790

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
22-52

[ RIDADR ]:
NONH for all modes of transport


Related Compounds