Obtusifolin-2-O-glucoside

Names

[ CAS No. ]:
120163-18-0

[ Name ]:
Obtusifolin-2-O-glucoside

[Synonym ]:
Obtusifolin 2-glucoside
gluco-obtusifolin

Biological Activity

[Description]:

Obtusifolin-2-O-glucoside (compound 7) is a Tyrosinase inhibitor (IC50=9.2 μM). Obtusifolin-2-O-glucoside can be isolated from cassia seed[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Metabolic Enzyme/Protease >> Tyrosinase

[Target]

IC50: 9.2 μM (Tyrosinase)[1]


[In Vitro]

Obtusifolin-2-O-glucoside (化合物 7) (10 μM; 48 h) 抑制α-MSH处理的B16F10黑色素瘤细胞中的黑素生成[1]。

[References]

[1]. Lee GY, et al. Tyrosinase inhibitory components from the seeds of Cassia tora. Arch Pharm Res. 2018 May;41(5):490-496.  

Chemical & Physical Properties

[ Density]:
1.567g/cm3

[ Boiling Point ]:
790.3ºC at 760 mmHg

[ Molecular Formula ]:
C22H22O10

[ Molecular Weight ]:
446.40400

[ Flash Point ]:
278.2ºC

[ Exact Mass ]:
446.12100

[ PSA ]:
162.98000

[ Vapour Pressure ]:
2.51E-26mmHg at 25°C

[ Index of Refraction ]:
1.68

Related Compounds