Fullerene-C60

Names

[ Name ]:
Fullerene-C60

[Synonym ]:
Fullerene-C60
(5,6)Fullerene-C60-Ih
(C60-Ih)[5,6]Fullerene
FULLEREN C60
MFCD00151408
Buckminsterfullerene
[60]Fullerene
[5,6]Fullerene-C60
FULLERENE
fullerene C60
FULLERENC60
C60
Buckminsterfullerene, C60
FULLERENE POWDER C

Biological Activity

[Description]:

Fullerene-C60, a representative of carbon nanocompounds, is suggested to be promising agent for application in photodynamic therapy due to its unique physicochemical properties. Fullerene-C60 probes the intramolecular dynamics of its electron and energy transfer[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[In Vitro]

High affinity of fullerene core for electron donors determines its ability to be a scavenger of free radicals. On the other hand, C60 molecule is able to absorb effectively UV and visible light with further transition to the first singlet excited state, then to a long-lived triplet excited state and subsequent energy transfer to molecular oxygen-yielding singlet oxygen with quantum yield close to 100%[1].

[References]

[1]. D Franskevych,et al. Fullerene C 60 Penetration into Leukemic Cells and Its Photoinduced Cytotoxic Effects. Nanoscale Res Lett.2017 Dec;12(1):40.

Chemical & Physical Properties

[ Density]:
3.4±0.1 g/cm3

[ Boiling Point ]:
500-600℃ subl.

[ Melting Point ]:
>280ºC(lit.)

[ Molecular Formula ]:
C₆₀

[ Molecular Weight ]:
720.642

[ Flash Point ]:
94ºC

[ Exact Mass ]:
720.000000

[ LogP ]:
21.59

[ Index of Refraction ]:
1.813

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37

[ Safety Phrases ]:
26-36

[ RIDADR ]:
UN1325

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
4.1

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

Preparation and characterization of fullerene (C60) amino acid nanoparticles for liver cancer cell treatment.

J. Nanosci. Nanotechnol. 14(6) , 4513-8, (2014)

The properties of an ideal photosensitizer are water solubility, low cytotoxicity in the dark, high ability to produce reactive oxygen species (ROS). The characteristics of water-soluble fullerene (C6...

Biochemical and hematologic effects of polyvinylpyrrolidone-wrapped fullerene C60 after oral administration.

Pharmazie 68(1) , 54-7, (2013)

The fullerene C60 is used in consumer products such as cosmetics owing to its antioxidative effects and is being developed for nanomedical applications. However, knowledge regarding the safety of full...

Effect of C60 fullerenes on the accumulation of weathered p,p'-DDE by plant and earthworm species under single and multispecies conditions.

Environ. Toxicol. Chem. 32(5) , 1117-23, (2013)

The use of engineered nanomaterials has increased dramatically in recent years, but an understanding of nanomaterial fate and effects in the environment is lacking. In particular, the interaction of n...