Valosin Peptide (VQY), porcine

Names

[ Name ]:
Valosin Peptide (VQY), porcine

[Synonym ]:
Peptide VQY
Val-Gln-Tyr-Pro-Val-Glu-His-Pro-Asp-Lys-Phe-Leu-Lys-Phe-Gly-Met-Thr-Pro-Ser-Lys-Gly-Val-Leu-Phe-Tyr
MFCD00133919
Valosin Peptide (VQY), porcine

Biological Activity

[Description]:

Valosin (porcine) is a biologically active peptide with 25-amino-acid. Valosin (porcine) can be isolated recently from pig intestine. Valosin (porcine) can be used for the research of digestive system[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

[References]

[1]. K J Koller, et al. Use of a cDNA clone to identify a supposed precursor protein containing valosin. Nature. 1987 Feb 5-11;325(6104):542-5.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₄₁H₂₀₇N₃₁O₃₅S

[ Molecular Weight ]:
2928.40000

[ Exact Mass ]:
2926.51000

[ PSA ]:
1066.00000

[ LogP ]:
7.10790

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Valosin: isolation and characterization of a novel peptide from porcine intestine.

FEBS Lett. 191 , 264, (1985)

The isolation and primary structure of a novel gastrointestinal peptide, designated valosin, is described. The peptide was purified from porcine upper gut extracts using an HPLC and N-terminal sequenc...

The structural and functional basis of the p97/valosin-containing protein (VCP)-interacting motif (VIM): mutually exclusive binding of cofactors to the N-terminal domain of p97.

J. Biol. Chem. 286 , 38679-38690, (2011)

The AAA (ATPase associated with various cellular activities) ATPase p97, also referred to as valosin-containing protein (VCP), mediates essential cellular processes, including ubiquitin-dependent prot...

Valosin stimulates gastric and exocrine pancreatic secretion and inhibits fasting small intestinal myoelectric activity in the dog. Konturek SJ, Schmidt WE, et al.

Gastroenterol. Clin. Biol. 92 , 1181-1186, (1987)