Betamethasone Acetate

Names

[ CAS No. ]:
987-24-6

[ Name ]:
Betamethasone Acetate

[Synonym ]:
Betamethasone acetate
MFCD00867462
(11β,16β)-9-Fluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl acetate
Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-16-methyl-21-(acetyloxy)-, (11β,16β)-
Betafluorene
Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-9-fluoro-11,17-dihydroxy-16-methyl-, (11β,16β)-
UNII-TI05AO53L7
2-[(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl acetate
9-Fluoro-11b,17,21-trihydroxy-16b-methylpregna-1,4-diene-3,20-dione 21-Acetate
EINECS 213-578-6
Betamethasone 21-acetate

Biological Activity

[Description]:

Betamethasone acetate is a glucocorticoid corticosteroid. Betamethasone acetate induces fetal lung maturation in preterm sheep[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[References]

[1]. Schmidt AF, et al. Low-dose betamethasone-acetate for fetal lung maturation in preterm sheep. Am J Obstet Gynecol. 2018 Jan;218(1):132.e1-132.e9.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
579.4±50.0 °C at 760 mmHg

[ Melting Point ]:
200-220°C (dec.)

[ Molecular Formula ]:
C₂₄H₃₁FO₆

[ Molecular Weight ]:
434.498

[ Flash Point ]:
304.2±30.1 °C

[ Exact Mass ]:
434.210480

[ PSA ]:
100.90000

[ LogP ]:
2.96

[ Vapour Pressure ]:
0.0±3.6 mmHg at 25°C

[ Index of Refraction ]:
1.571

[ Storage condition ]:
Refrigerator

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS08

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H351

[ Precautionary Statements ]:
P280

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R40

[ Safety Phrases ]:
S22-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

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