6-(2,3-dichlorophenyl)-3-imino-2-propan-2-yl-1,2,4-triazin-5-amine
Names
[ CAS No. ]:
98410-36-7
[ Name ]:
6-(2,3-dichlorophenyl)-3-imino-2-propan-2-yl-1,2,4-triazin-5-amine
[Synonym ]:
Palatrigine
1,2,4-Triazin-3-amine,6-(2,3-dichlorophenyl)-2,5-dihydro-5-imino-2-(1-methylethyl)
2,5-Dihydro-6-(2,3-dichlorophenyl)-5-imino-2-(1-methylethyl)-1,2,4-triazin-3-amine
1,2,4-Triazin-3-amine,2,5-dihydro-6-(2,3-dichlorophenyl)-5-imino-2-(1-methylethyl)
Palatriginum [Latin]
Palatrigina [Spanish]
Palatrigina
Palatriginum
Bwa 256C
Chemical & Physical Properties
[ Density]:
1.49g/cm3
[ Boiling Point ]:
402.1ºC at 760 mmHg
[ Molecular Formula ]:
C12H13Cl2N5
[ Molecular Weight ]:
298.17100
[ Flash Point ]:
197ºC
[ Exact Mass ]:
297.05500
[ PSA ]:
80.58000
[ LogP ]:
3.57540
[ Index of Refraction ]:
1.681
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- XY2892000
- CHEMICAL NAME :
- 1,2,4-Triazin-3-amine, 2,5-dihydro-6-(2,3-dichlorophenyl)-5-imino-2-(1-methy lethyl)-
- CAS REGISTRY NUMBER :
- 98410-36-7
- LAST UPDATED :
- 199410
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C12-H13-Cl2-N5
- MOLECULAR WEIGHT :
- 298.20
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 229 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 12,621,1987
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 25500 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 12,621,1987
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 8340 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 12,621,1987
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 204 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 12,621,1987
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 17900 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 12,621,1987
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 4880 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 12,621,1987