Tanshindiol B

Names

[ CAS No. ]:
97465-70-8

[ Name ]:
Tanshindiol B

[Synonym ]:
Tanshindiol B
Phenanthro[1,2-b]furan-10,11-dione, 6,7,8,9-tetrahydro-6,7-dihydroxy-1,6-dimethyl-, (6R-cis)-

Biological Activity

[Description]:

Tanshindiol B, a naphthaquinone diterpene, inhibits GBM growth by induction of noptosis (NQO1-dependent necrosis)[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[In Vitro]

Tanshindiol B (TSB) 触发明显的细胞死亡，不属于凋亡，而是氧化应激引起的坏死。

[References]

[1]. A Yagi, et al. Effect of abietane- type pigments from Salvia miltiorrhiza on post-hypoxic recovery of cardiac contractile force in rats. Planta Med. 1991 Jun;57(3):288-9.

Chemical & Physical Properties

[ Density]:
1.436±0.06 g/cm3(20 °C , 760mmHg)

[ Boiling Point ]:
561.5±50.0 °C (760 mmHg)

[ Molecular Formula ]:
C₁₈H₁₆O₅

[ Molecular Weight ]:
312.31700

[ Exact Mass ]:
312.10000

[ PSA ]:
87.74000

[ LogP ]:
2.14860

Related Compounds

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