alpha,alpha-diphenylpiperidine-1-propanol hydrochloride
Names
[ CAS No. ]:
968-58-1
[ Name ]:
alpha,alpha-diphenylpiperidine-1-propanol hydrochloride
[Synonym ]:
Mitanoline
1,1-diphenyl-3-(piperidin-1-yl)propan-1-ol hydrochloride(1:1)
3-Piperidino-1,1-diphenyl-1-propanol hydrochloride
1,1-diphenyl-3-piperidino-propan-1-ol,hydrochloride
Pridinol hydrochloride
Pridinol-hydrochlorid
EINECS 213-529-9
Par KS-12
1,1-Diphenyl-3-piperidino-propan-1-ol,Hydrochlorid
1,1-Diphenyl-3-piperidino-1-propanol hydrochloride
Chemical & Physical Properties
[ Density]:
1.079g/cm3
[ Boiling Point ]:
460.9ºC at 760mmHg
[ Melting Point ]:
120-121ºC
[ Molecular Formula ]:
C20H26ClNO
[ Molecular Weight ]:
331.88000
[ Flash Point ]:
229.9ºC
[ Exact Mass ]:
331.17000
[ PSA ]:
23.47000
[ LogP ]:
4.53840
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TN2856000
- CHEMICAL NAME :
- 1-Piperidinepropanol, alpha,alpha-diphenyl-, hydrochloride
- CAS REGISTRY NUMBER :
- 968-58-1
- LAST UPDATED :
- 199606
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C20-H25-N-O.Cl-H
- MOLECULAR WEIGHT :
- 331.92
- WISWESSER LINE NOTATION :
- T6NTJ A2XQR&R &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 91 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 96,151,1949
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 33 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 96,151,1949
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 131 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 96,151,1949
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 25 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 116,177,1956 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 1500 mg/kg/15W-I
- TOXIC EFFECTS :
- Behavioral - irritability
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 96,151,1949
Safety Information
[ HS Code ]:
2933399090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933399090
[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%