(Des-Gly10,D-Arg6,Pro-NHEt9)-LHRH (salmon) acetate salt

Names

[ Name ]:
(Des-Gly10,D-Arg6,Pro-NHEt9)-LHRH (salmon) acetate salt

[Synonym ]:
[D-Arg6,Pro9-NEt]Salmon GnRH
(DES-GLY10,D-ARG6,PRO-NHET9)-LHRH (SALMON)
[D-Arg6,Pro9-NEt]Salmon gonadotropin-releasing hormone

Biological Activity

[Description]:

sGnRH-A is a salmon gonadotropin-releasing hormone (GnRH) analogue that stimulates growth hormone secretion and can also be used as an inducer of ovulation by artificial insemination[1][2].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> GNRH Receptor

Research Areas >> Endocrinology

[In Vitro]

sGnRH-A (0.1 nM-1 μM, 24 h) increases GH mRNA levels and stimulates GH secretion in a dose-dependent manner, and induces growth hormone levels nearly 5 times higher than the control at 10 nM when incubated for 6 h in common carp pituitary fragments[1].

Chemical & Physical Properties

[ Density]:
1.48±0.1 g/cm3 (20 °C, 760 mmHg)

[ Molecular Formula ]:
C₆₄H₈₃N₁₇O₁₂

[ Molecular Weight ]:
1282.45000

[ Exact Mass ]:
1281.64000

[ PSA ]:
444.83000

[ LogP ]:
4.03430