Berkeleyacetal C

Names

[ Name ]:
Berkeleyacetal C

Biological Activity

[Description]:

Berkeleyacetal C, a meroterpenoid compound, shows favorable activity of inhibiting nitrogen oxide (NO) production of macrophages stimulated by lipopolysaccharide (LPS). Berkeleyacetal C exerts anti-inflammatory effects via inhibiting NF-κB, ERK1/2 and IRF3 signaling pathways[1].

[Related Catalog]:

Signaling Pathways >> Anti-infection >> Fungal

Research Areas >> Inflammation/Immunology

[Target]

Microbial Metabolite

[References]

[1]. Li SS, et al. Berkeleyacetal C, a meroterpenoid isolated from the fungus Penicillium purpurogenum MHZ 111, exerts anti-inflammatory effects via inhibiting NF-κB, ERK1/2 and IRF3 signaling pathways. Eur J Pharmacol. 2017;814:283-293.

[2]. Márquez-Cadena MA, et al. Synthetic Studies toward the Berkeleyacetal Core Architecture. Org Lett. 2021 Nov 15.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₄H₂₆O₈

[ Molecular Weight ]:
442.46

Related Compounds

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