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NVP-QAV-572

Names

[ CAS No. ]:
957209-68-6

[ Name ]:
NVP-QAV-572

[Synonym ]:
nvp-qav-572

Biological Activity

[Description]:

NVP-QAV-572 is a PI3K inhibitor extracted from patent US7998990B2, Compound Example 8, has an IC50 of 10 nM.

[Related Catalog]:

Research Areas >> Cancer

[Target]

PI3K:10 nM (IC50)


[In Vitro]

NVP-QAV-572 (Example 8) is useful in the treatment of conditions which are mediated by the activation of the Pi3 kinase enzymes, particularly inflammatory or allergic conditions[1].

[References]

[1]. Emma Budd, et al. 5-phenyl-thiazol-2-yl-urea derivatives and use as PI3 kinase inhibitors. US 7998990 B2.


[Related Small Molecules]

3-Methyladenine | LY294002 | Wortmannin | Alpelisib (BYL719) | BKM120 | Eganelisib(IPI-549) | BAY 80-6946 (Copanlisib) | Idelalisib (CAL-101) | Dactolisib (BEZ235) | Quercetin | SAR-405 | GDC-0941 | 740 Y-P | LY3023414 | 1,3-Dicaffeoylquinic acid

Chemical & Physical Properties

[ Density]:
1.59±0.1 g/cm3 (20 °C, 760 mmHg)

[ Molecular Formula ]:
C17H19F2N7O3S2

[ Molecular Weight ]:
471.50500

[ Exact Mass ]:
471.09600

[ PSA ]:
168.38000

[ LogP ]:
3.52600

[ Storage condition ]:
2-8℃

Related Compounds

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