Cochinchinenin C

Names

[ Name ]:
Cochinchinenin C

[Synonym ]:
3-{4-Hydroxy-5-[3-(4-hydroxy-2-methoxyphenyl)-1-(4-methoxyphenyl)propyl]-2-methoxyphenyl}-1-(4-hydroxyphenyl)propan-1-one
Loureirin C
3-{4-Hydroxy-5-[3-(4-hydroxy-2-methoxyphenyl)-1-(4-methoxyphenyl)propyl]-2-methoxyphenyl}-1-(4-hydroxyphenyl)-1-propanone
1-Propanone, 3-[4-hydroxy-5-[3-(4-hydroxy-2-methoxyphenyl)-1-(4-methoxyphenyl)propyl]-2-methoxyphenyl]-1-(4-hydroxyphenyl)-

Biological Activity

[Description]:

Cochinchinenin C is a nonpolypeptide agonist of glucagon-like peptide-1 (GLP-1) receptor. Cochinchinenin C can be used for the research of diabetes[1][2].

[Related Catalog]:

Research Areas >> Metabolic Disease

Signaling Pathways >> GPCR/G Protein >> Glucagon Receptor

[Target]

glucagon-like peptide-1 receptor[1][2]

[References]

[1]. Sha Y et, al. Cochinchinenin C, a potential nonpolypeptide anti-diabetic drug, targets a glucagon-like peptide-1 receptor. RSC Adv., 2017, 7, 49015-49023.

[2]. Chen X, et, al. Comparison between loureirin A and cochinchinenin C on the interaction with human serum albumin. Eur J Med Chem. 2015 Mar 26;93:492-500.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
767.2±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C₃₃H₃₄O₇

[ Molecular Weight ]:
542.619

[ Flash Point ]:
247.5±26.4 °C

[ Exact Mass ]:
542.230469

[ PSA ]:
105.45000

[ LogP ]:
6.26

[ Vapour Pressure ]:
0.0±2.7 mmHg at 25°C

[ Index of Refraction ]:
1.619

Related Compounds

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