<Suppliers Price>

VK-II-36

Names

[ CAS No. ]:
955371-66-1

[ Name ]:
VK-II-36

[Synonym ]:
6-[(9H-Carbazol-4-yloxy)methyl]-4-[2-(2-methoxyphenoxy)ethyl]-3-morpholinone
3-Morpholinone, 6-[(9H-carbazol-4-yloxy)methyl]-4-[2-(2-methoxyphenoxy)ethyl]-
VK-II-36

Biological Activity

[Description]:

VK-II-36 is a carvedilol analog that suppresses sarcoplasmic reticulum Ca2+release but does not block the β-receptor.VK-II-36 inhibits triggered activities evoked by both early and delayed after depolarizations[1].

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> Calcium Channel
Research Areas >> Cardiovascular Disease

[References]

[1]. Maruyama M, et al. Carvedilol analogue inhibits triggered activities evoked by both early and delayed afterdepolarizations. Heart Rhythm. 2013 Jan;10(1):101-7.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
698.6±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C26H26N2O5

[ Molecular Weight ]:
446.50

[ Flash Point ]:
376.3±31.5 °C

[ Exact Mass ]:
446.184174

[ LogP ]:
4.25

[ Vapour Pressure ]:
0.0±2.2 mmHg at 25°C

[ Index of Refraction ]:
1.644

Related Compounds