2-Amino-4-chlorophenol
Names
[ CAS No. ]:
95-85-2
[ Name ]:
2-Amino-4-chlorophenol
[Synonym ]:
EINECS 202-458-9
2-Amino-4-chlorophenol
5-Chloro-2-hydroxyaniline
Phenol, 2-amino-4-chloro-
MFCD00007694
Chemical & Physical Properties
[ Density]:
1.4±0.1 g/cm3
[ Boiling Point ]:
276.8±25.0 °C at 760 mmHg
[ Melting Point ]:
136-141 °C(lit.)
[ Molecular Formula ]:
C6H6ClNO
[ Molecular Weight ]:
143.571
[ Flash Point ]:
121.2±23.2 °C
[ Exact Mass ]:
143.013794
[ PSA ]:
46.25000
[ LogP ]:
1.67
[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C
[ Index of Refraction ]:
1.651
[ Water Solubility ]:
Insoluble.
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- SJ5700000
- CHEMICAL NAME :
- Phenol, 2-amino-4-chloro-
- CAS REGISTRY NUMBER :
- 95-85-2
- BEILSTEIN REFERENCE NO. :
- 0774859
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C6-H6-Cl-N-O
- MOLECULAR WEIGHT :
- 143.58
- WISWESSER LINE NOTATION :
- ZR BQ EG
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 690 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1030 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA
- TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 333 ug/plate
- REFERENCE :
- EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 11(Suppl 12),1,1988 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 82099 No. of Facilities: 28 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 168 (estimated)
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302-H315-H319-H335
[ Precautionary Statements ]:
P301 + P312 + P330-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xn:Harmful;
[ Risk Phrases ]:
R22;R36/37/38
[ Safety Phrases ]:
S26-S36-S36/37/39
[ RIDADR ]:
UN 2673 6.1/PG 2
[ WGK Germany ]:
3
[ RTECS ]:
SJ5700000
[ Packaging Group ]:
II
[ Hazard Class ]:
6.1
[ HS Code ]:
29222900
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2922299090
[ Summary ]:
2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
Articles
Microb. Cell Fact. 11 , 150, (2012)
Chloronitrophenols (CNPs) are widely used in the synthesis of dyes, drugs and pesticides, and constitute a major group of environmental pollutants. 4-Chloro-2-nitrophenol (4C2NP) is an isomer of CNPs ...
A new way for synthesis of phenoxazine and diphenoxazine derivatives via electrochemical method.Chem. Pharm. Bull. 59(10) , 1209-13, (2011)
Electrochemical oxidation of hydroquinone (1a) and 2,3-dimethylhydroquinone (1b) have been studied in the presence of 2-aminophenol (3a) and 2-amino-4-chlorophenol (3b), as nucleophiles in phosphate b...
Stability-indicating TLC-densitometric method for simultaneous determination of paracetamol and chlorzoxazone and their toxic impurities.J. Chromatogr. Sci. 51(2) , 187-91, (2013)
A highly sensitive, selective and accurate thin-layer chromatographic (TLC)-densitometric method has been developed and validated for the simultaneous determination of paracetamol (PAR) and chlorzoxaz...