2,5-Dichloroaniline
Names
[ CAS No. ]:
95-82-9
[ Name ]:
2,5-Dichloroaniline
[Synonym ]:
2,5-DICHLORO-BENZENAMINE
2,5-dichloro
Azobase DCA
2,5-dichlorophenylamine
scarletbasengg
2,5-DICHLOROANILINE D
1-amino-2,5-dichlorobenzene
2,5-DI CHLORO ANILINE
fastredsggbase
Benzenamine, 2,5-dichloro-
EINECS 202-455-2
2,5-Dichloroaniline
2,5-DICHLORANILIN
scarletbasegg
MFCD00007667
2,5-dichloro-aniline
1,4-Dichloro-2-aminobenzene
2,5-DICHLOROANILINE FOR SYNTHESIS
SearletbaseGGS
2,4-DICHLOROQUINOLINE
Chemical & Physical Properties
[ Density]:
1.4±0.1 g/cm3
[ Boiling Point ]:
251.0±0.0 °C at 760 mmHg
[ Melting Point ]:
48 °C
[ Molecular Formula ]:
C6H5Cl2N
[ Molecular Weight ]:
162.017
[ Flash Point ]:
100.4±21.8 °C
[ Exact Mass ]:
160.979904
[ PSA ]:
26.02000
[ LogP ]:
2.71
[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C
[ Index of Refraction ]:
1.614
[ Water Solubility ]:
ca. 0.56 g/L (20 ºC)
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- BX2610000
- CHEMICAL NAME :
- Aniline, 2,5-dichloro-
- CAS REGISTRY NUMBER :
- 95-82-9
- BEILSTEIN REFERENCE NO. :
- 1447438
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 13
- MOLECULAR FORMULA :
- C6-H5-Cl2-N
- MOLECULAR WEIGHT :
- 162.02
- WISWESSER LINE NOTATION :
- ZR BG EG
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1600 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TSCAT* Office of Toxic Substances Report. (U.S. Environmental Protection Agency, Office of Toxic Substances, 401 M St., SW, Washington, DC 20460) Volume(issue)/page/year: OTS 206512
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 400 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TSCAT* Office of Toxic Substances Report. (U.S. Environmental Protection Agency, Office of Toxic Substances, 401 M St., SW, Washington, DC 20460) Volume(issue)/page/year: OTS 206512
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1600 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TSCAT* Office of Toxic Substances Report. (U.S. Environmental Protection Agency, Office of Toxic Substances, 401 M St., SW, Washington, DC 20460) Volume(issue)/page/year: OTS 206512
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 400 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TSCAT* Office of Toxic Substances Report. (U.S. Environmental Protection Agency, Office of Toxic Substances, 401 M St., SW, Washington, DC 20460) Volume(issue)/page/year: OTS 206512
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 56 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#00202
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 3750 mg/kg
- TOXIC EFFECTS :
- Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - cyanosis
- REFERENCE :
- GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 33(4),8,1968
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 3750 mg/kg
- TOXIC EFFECTS :
- Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - cyanosis
- REFERENCE :
- GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 33(4),8,1968 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 27300 mg/kg/13W-I
- TOXIC EFFECTS :
- Endocrine - changes in spleen weight Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - catalases
- REFERENCE :
- GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 33(4),8,1968 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4027 No. of Facilities: 116 (estimated) No. of Industries: 3 No. of Occupations: 6 No. of Employees: 2820 (estimated) No. of Female Employees: 246 (estimated)
Safety Information
[ Symbol ]:
GHS06, GHS08, GHS09
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H301 + H311 + H331-H373-H410
[ Precautionary Statements ]:
P261-P273-P280-P301 + P310-P311-P501
[ Hazard Codes ]:
T:Toxic;N:Dangerousfortheenvironment;
[ Risk Phrases ]:
R23/24/25;R33;R50/53
[ Safety Phrases ]:
S28-S36/37-S45-S60-S61-S28A
[ RIDADR ]:
UN 3442 6.1/PG 2
[ WGK Germany ]:
3
[ RTECS ]:
BX2610000
[ Packaging Group ]:
II
[ Hazard Class ]:
6.1
[ HS Code ]:
2921420090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2921420090
[ Summary ]:
HS:2921420090 aniline derivatives and their salts VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
Articles
Synthetic Metals 118(1-3) , 25-31, (2001)
Tautomeric properties and crystal structure of N−[2−hydroxy−1−naphthylidene] 2,5−dichloroaniline. Yildiz M, et al.
Cryst. Res. Technol. 41(6) , 600-606, (2006)
Determination of aromatic amines by solid-phase microextraction and gas chromatography−mass spectrometry in water samples. Muller L, et al.
J. Chromatogr. A. 791(1) , 221-230, (1997)