Bruceine J

Names

[ Name ]:
Bruceine J

[Synonym ]:
(11β,12α,15β)-3,11,12-Trihydroxy-15-[(3-methylbutanoyl)oxy]-2,16-dioxo-13,20-epoxypicras-3-en-21-oic acid
Picras-3-en-21-oic acid, 13,20-epoxy-3,11,12-trihydroxy-15-(3-methyl-1-oxobutoxy)-2,16-dioxo-, (11β,12α,15β)-

Biological Activity

[Description]:

Bruceine J, a quassinoid, is a nature product that could be isolated from fruits of Br. jaVanica. Bruceine J has anti-Babesial activity[1].

[Related Catalog]:

Research Areas >> Infection

[In Vitro]

Bruceine J (compond 2) 具有抗巴贝斯活性，对 babesia gibsoni 的 IC50 值为 742 ng/mL[1]。

[References]

[1]. Subeki, et, al. Screening of Indonesian medicinal plant extracts for antibabesial activity and isolation of new quassinoids from Brucea javanica. J Nat Prod. 2007 Oct;70(10):1654-7.

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
768.3±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₅H₃₂O₁₁

[ Molecular Weight ]:
508.515

[ Flash Point ]:
260.2±26.4 °C

[ Exact Mass ]:
508.194458

[ LogP ]:
1.34

[ Vapour Pressure ]:
0.0±5.9 mmHg at 25°C

[ Index of Refraction ]:
1.619

Related Compounds

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