HT-0411

Names

[ Name ]:
HT-0411

Biological Activity

[Description]:

A selective monoamine oxidase B (MAO-B) inhibitor with IC50 of 1.4 uM, with less potency for MT-1 and MT-2; causes CREB activation in vitro, improves 24-hour memory in rodents in a contextual fear conditioning model.

[References]

References 1. Kaplan A, et al. ACS Chem Neurosci. 2017 Dec 20;8(12):2746-2758. View Related Products by Target Monoamine Oxidase (MAO)

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₂H₁₂F₃N₃OS

[ Molecular Weight ]:
303.303

Related Compounds

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