2-Bromo-5-fluorobenzaldehyde

Names

[ Name ]:
2-Bromo-5-fluorobenzaldehyde

[Synonym ]:
VHR CF FE
2-bromo-5-fluoro-benzaldehyde
Benzaldehyde, 2-bromo-5-fluoro-
VHR DF CE
Benzaldehyde, 3-bromo-4-fluoro-
3-Brom-4-fluorbenzolcarbaldehyd
MFCD00142872
2-Bromo-5-fluorobenzaldehyde
5-FLUORO-2-BROMO BENZALDEHYDE
2-bromo-5-fluorophenyl carbaldehyde
2-bromo-5-flurobenzaldehyde
Benzaldehyde,2-bromo-5-fluoro
2-bromo-5-fluorobenzaldhyde
3-Bromo-4-fluorobenzaldehyde

Chemical & Physical Properties

[ Density]:
1.7±0.1 g/cm3

[ Boiling Point ]:
225.8±20.0 °C at 760 mmHg

[ Melting Point ]:
51-56 °C(lit.)

[ Molecular Formula ]:
C₇H₄BrFO

[ Molecular Weight ]:
203.008

[ Flash Point ]:
90.4±21.8 °C

[ Exact Mass ]:
201.942947

[ PSA ]:
17.07000

[ LogP ]:
2.64

[ Vapour Pressure ]:
0.1±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.585

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36/37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2913000090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2913000090

[ Summary ]:
HS: 2913000090 halogenated, sulphonated, nitrated or nitrosated derivatives of products of heading 2912 Educational tariff:17.0% Tax rebate rate:9.0% Regulatory conditions:none Most favored nation tariff:5.5% General tariff:30.0%

Articles

5-Fluoro-1,3-dihydro-2,1-benzoxaborol-1-ol.

Acta Crystallogr. Sect. E Struct. Rep. Online 67(Pt 2) , o414-5, (2011)

In the crystal structure of the title compound, C(7)H(6)BFO(2), a broad-spectrum anti-fungal drug (AN2690), the planar [maximum deviation 0.035 (1) Å] mol-ecules form centrosymmetric R(2) (2)(8) dimer...

Discovery of a new boron-containing antifungal agent, 5-fluoro-1,3-dihydro-1-hydroxy-2,1- benzoxaborole (AN2690), for the potential treatment of onychomycosis.

J. Med. Chem. 49(15) , 4447-50, (2006)

A structure-activity relationship investigation for a more efficacious therapy to treat onychomycosis, a fungal infection of the toe and fingernails, led to the discovery of a boron-containing small m...

2-Bromo-5-fluorobenzaldehyde. Tureski RE and Tanski JM.

Acta Crystallogr. Sect. E Struct. Rep. Online 69(8) , o1246-o1246, (2013)