Rhuscholide A

Names

[ Name ]:
Rhuscholide A

[Synonym ]:
5-Hydroxy-3-isopropylidene-7-[(2E,6E,10E)-3,7,11,15-tetramethyl-2,6,10,14-hexadecatetraen-1-yl]-1-benzofuran-2(3H)-one
2(3H)-Benzofuranone, 5-hydroxy-3-(1-methylethylidene)-7-[(2E,6E,10E)-3,7,11,15-tetramethyl-2,6,10,14-hexadecatetraen-1-yl]-

Biological Activity

[Description]:

Rhuscholide A is a benzofuran lactone that shows significant anti-HIV-1 activity, with an EC50 of 1.62 μM[1].

[Related Catalog]:

Signaling Pathways >> Anti-infection >> HIV

Research Areas >> Infection

[References]

[1]. Gu Q, et, al. A new benzofuranone and anti-HIV constituents from the stems of Rhus chinensis. Planta Med. 2007 Mar;73(3):279-82.

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
604.7±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C₃₁H₄₂O₃

[ Molecular Weight ]:
462.66

[ Flash Point ]:
227.0±24.3 °C

[ Exact Mass ]:
462.313385

[ PSA ]:
46.53000

[ LogP ]:
10.70

[ Vapour Pressure ]:
0.0±1.8 mmHg at 25°C

[ Index of Refraction ]:
1.550

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.