Meloxicam D4

Names

[ CAS No. ]:
942047-63-4

[ Name ]:
Meloxicam D4

[Synonym ]:
Parocin-d3
Metacam-d3
Movalis-d3
Movatec-d3
4-Hydroxy-2-(methyl-d3)-1,1-dioxo-benzo[e]-1,2-thiazine-3-carboxylic acid (5-methyl-2-thiazolyl)amide
Mobic-d3
Mobicox-d3
Meloxicam-d3

Biological Activity

[Description]:

Meloxicam D4 is deuterium labeled Meloxicam. Meloxicam is a non-steroidal antiinflammatory agent, inhibits COX activity, with IC50s of 0.49 µM and 36.6 µM for COX-2 and COX-1, respectively[1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis

Research Areas >> Cancer

Signaling Pathways >> Autophagy >> Autophagy

Research Areas >> Inflammation/Immunology

Signaling Pathways >> Immunology/Inflammation >> COX

[References]

[1]. Lazer ES, et al. Effect of structural modification of enol-carboxamide-type nonsteroidal antiinflammatory drugs on COX-2/COX-1 selectivity. J Med Chem. 1997 Mar 14;40(6):980-9.

Chemical & Physical Properties

[ Melting Point ]:
249-251°C

[ Molecular Formula ]:
C₁₄H₁₀D₃N₃O₄S₂

[ Molecular Weight ]:
351.40100

[ Exact Mass ]:
351.03500

[ PSA ]:
139.71000

[ LogP ]:
3.61910

[ Storage condition ]:
-20°C Freezer

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301

[ Precautionary Statements ]:
P301 + P310

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
22

[ RIDADR ]:
UN 2811 6.1/PG 3

Related Compounds

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