H 151

Names

[ CAS No. ]:
941987-60-6

[ Name ]:
H 151

Biological Activity

[Description]:

H-151 is a highly potent, selective and covalent antagonist of STING, reduces TBK1 phosphorylation and suppresses human STING palmitoylation[1].

[Related Catalog]:

Research Areas >> Inflammation/Immunology

Signaling Pathways >> Immunology/Inflammation >> STING

[Target]

STING[1]

[References]

[1]. Haag SM, et al. Targeting STING with covalent small-molecule inhibitors. Nature. 2018 Jul;559(7713):269-273.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₇H₁₇N₃O

[ Molecular Weight ]:
279.34

[ Storage condition ]:
2-8℃

Related Compounds

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