OB 24 hydrochloride

Names

[ Name ]:
OB 24 hydrochloride

Biological Activity

[Description]:

OB-24 is a potent inhibitor of heme oxygenase-1 (HO-1). Heme oxygenase-1, a member of the heat shock protein family, plays a key role as a sensor and regulator of oxidative stress. OB-24 significantly inhibited cell proliferation in vitro and tumor growth and lymph node/lung metastases in vivo. OB-24 has potential for the research of advanced prostate cancer (PCA)[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[References]

[1]. Alaoui-Jamali MA, et al. A novel experimental heme oxygenase-1-targeted therapy for hormone-refractory prostate cancer. Cancer Res. 2009;69(20):8017-8024.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₅H₁₇BrN₂O_2.HCl

[ Molecular Weight ]:
373.67

[ Storage condition ]:
Store at -20°C

Related Compounds

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