CETP-IN-3

Names

[ CAS No. ]:
939391-31-8

[ Name ]:
CETP-IN-3

Biological Activity

[Description]:

CETP-IN-3 (Compound 13) is an small molecule inhibitor of the plasma glycoprotein cholesterol ester transfer protein (CETP), elevating HDL-C through inhibition of CETP. CETP-IN-3 for the CETP inhibitory activity in the scintillation proximity (SPA) and whole plasma assay (WPA) with IC50s of 0.002 μM and 0.06 μM, respectively[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease
Signaling Pathways >> Metabolic Enzyme/Protease >> CETP

[References]

[1]. Finlay HJ, et al. Discovery of a Lead Triphenylethanamine Cholesterol Ester Transfer Protein (CETP) Inhibitor. ACS Med Chem Lett. 2019 May 6; 10(6):911-916.

Chemical & Physical Properties

[ Molecular Formula ]:
C30H24F12N2O4

[ Molecular Weight ]:
704.50

Related Compounds