Nifeviroc

Names

[ CAS No. ]:
934740-33-7

[ Name ]:
Nifeviroc

[Synonym ]:
MFCD28502080

Biological Activity

[Description]:

Nifeviroc is an orally active CCR5 antagonist. Nifeviroc is used for the study of HIV type-1 infection[1].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> CCR

Signaling Pathways >> Anti-infection >> HIV

Research Areas >> Infection

Signaling Pathways >> Immunology/Inflammation >> CCR

Research Areas >> Inflammation/Immunology

[Target]

CCR5

HIV-1

[References]

[1]. Wei Wu, et al. Determination of nifeviroc, a novel CCR5 antagonist: application to a pharmacokinetic study. J Pharm Biomed Anal. 2011 Nov 1;56(3):637-40.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
761.1±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C₃₃H₄₂N₄O₆

[ Molecular Weight ]:
590.710

[ Flash Point ]:
414.1±32.9 °C

[ Exact Mass ]:
590.310425

[ LogP ]:
5.20

[ Vapour Pressure ]:
0.0±2.7 mmHg at 25°C

[ Index of Refraction ]:
1.631

[ Storage condition ]:
2-8°C

Related Compounds

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