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Karavilagenin D

Names

[ CAS No. ]:
934739-29-4

[ Name ]:
Karavilagenin D

[Synonym ]:
(1R,4S,5S,8R,9R,12S,13S,16S)-16-Hydroxy-8-[(2R,4E)-6-hydroxy-6-methyl-4-hepten-2-yl]-5,9,17,17-tetramethyl-18-oxapentacyclo[10.5.2.0.0.0]nonadec-2-en-19-one
5,9-(Epoxymethano)-2H-cyclopenta[a]phenanthren-18-one, 1,3,4,8,10,11,12,13,14,15,16,17-dodecahydro-3-hydroxy-17-[(1R,3E)-5-hydroxy-1,5-dimethyl-3-hexen-1-yl]-4,4,13,14-tetramethyl-, (3S,5R,8S,9S,10S,13R,14S,17R)-

Biological Activity

[Description]:

Karavilagenin D, a cucurbitane-type triterpene isolated from Japanese bitter melon leaves, is a potential tumor-promoting inhibitor[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[References]

[1]. Jie Zhang, et al. Cucurbitane triterpenoids from the leaves of Momordica charantia, and their cancer chemopreventive effects and cytotoxicities. Chem Biodivers. 2012 Feb;9(2):428-40.   

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
595.8±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C30H46O4

[ Molecular Weight ]:
470.684

[ Flash Point ]:
188.0±23.6 °C

[ Exact Mass ]:
470.339600

[ PSA ]:
66.76000

[ LogP ]:
5.83

[ Vapour Pressure ]:
0.0±3.8 mmHg at 25°C

[ Index of Refraction ]:
1.566

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds