BnO-PEG1-CH2COOH

Names

[ CAS No. ]:
93206-09-8

[ Name ]:
BnO-PEG1-CH2COOH

[Synonym ]:
7-phenyl-3,6-dioxaheptanoic acid

Biological Activity

[Description]:

BnO-PEG1-CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> PROTAC >> PROTAC Linker

[Target]

PEGs

[In Vitro]

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

[References]

[1]. Lepage ML, et al. Design, synthesis and photochemical properties of the first examples of iminosugar clustersbased on fluorescent cores. Beilstein J Org Chem. 2015 May 6;11:659-67.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₁H₁₄O₄

[ Molecular Weight ]:
210.22600

[ Exact Mass ]:
210.08900

[ PSA ]:
55.76000

[ LogP ]:
1.30440

Synthetic Route

Click to get detail synthetic route

Related Compounds

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