N-Benzyl-2-bromo-propionanilide
Names
[ CAS No. ]:
93010-41-4
[ Name ]:
N-Benzyl-2-bromo-propionanilide
[Synonym ]:
N-benzyl-N-phenyl-2-bromopropanamide
N-Benzyl-2-bromo-propionanilide
2-Bromo-N-phenyl-N-(phenylmethyl)propanamide
2-Brom-propionsaeure-(N-benzyl-anilid)
N-Benzyl-2-bromo-N-phenylpropionamide
(+-)-2-Brom-propionsaeure-(N-phenyl-benzylamid)
2-bromo-propionic acid-(N-benzyl-anilide)
Chemical & Physical Properties
[ Molecular Formula ]:
C16H16BrNO
[ Molecular Weight ]:
318.20800
[ Exact Mass ]:
317.04200
[ PSA ]:
20.31000
[ LogP ]:
4.00320
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302-H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ RIDADR ]:
UN 2923 6.1(8) / PGII
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Articles
J. Am. Chem. Soc. 127 , 4594, (2005)
A Ni/Pybox catalyst achieves the asymmetric cross-coupling of secondary alpha-bromo amides with organozinc reagents. The process tolerates a variety of functional groups and affords the desired produc...