o-Tolylbiguanide

Names

[ CAS No. ]:
93-69-6

[ Name ]:
o-Tolylbiguanide

[Synonym ]:
MFCD00019731
EINECS 202-268-6
o-Tolylbiguanide

Chemical & Physical Properties

[ Density]:
1.29 g/cm3

[ Boiling Point ]:
411.3ºCat 760 mmHg

[ Melting Point ]:
143-145 °C(lit.)

[ Molecular Formula ]:
C₉H₁₃N₅

[ Molecular Weight ]:
191.23300

[ Flash Point ]:
>230 °F

[ Exact Mass ]:
191.11700

[ PSA ]:
97.78000

[ LogP ]:
2.18840

[ Index of Refraction ]:
1.638

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DU2800000

CHEMICAL NAME :: Biguanide, 1-o-tolyl-

CAS REGISTRY NUMBER :: 93-69-6

BEILSTEIN REFERENCE NO. :: 0612193

LAST UPDATED :: 199701

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C9-H13-N5

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 800 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: IPSTB3 International Polymer Science and Technology. (Rapra Technology Ltd., Shawbury, Shrewsbury, Shropshire SY4 4NR, UK) Volume(issue)/page/year: 3,93,1976 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X2908 No. of Facilities: 80 (estimated) No. of Industries: 2 No. of Occupations: 2 No. of Employees: 886 (estimated) No. of Female Employees: 21 (estimated)

Safety Information

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H315-H318-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
R22

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
1

[ RTECS ]:
DU2800000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

[Method of determining o-tolylbiguanide in water].

Gig. Sanit. (5) , 45-6, (1984)

Bacalum E, et al.

Rev. Roum. Chim. 57(4-5) , 427-434, (2012)

New vanadyl complexes with metformin derivatives as potential insulin mimetic agents. Olar R, et al.

J. Therm. Anal. Calorim. 110(1) , 257-262, (2012)