AZD-7295

Names

[ CAS No. ]:
929890-64-2

[ Name ]:
AZD-7295

Biological Activity

[Description]:

AZD-7295 is a HCV NS5A protein inhibitor, with an EC50 of 7 nM for GT-1b replicon[1][2].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Metabolic Enzyme/Protease >> HCV Protease

Research Areas >> Inflammation/Immunology

[References]

[1]. Erik De Clercq, et al. Current race in the development of DAAs (direct-acting antivirals) against HCV. Biochem Pharmacol. 2014 Jun 15;89(4):441-52.

[2]. Min Gao, et al. Antiviral activity and resistance of HCV NS5A replication complex inhibitors. Curr Opin Virol. 2013 Oct;3(5):514-20.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₂H₃₅F₃N₄O₅S

[ Molecular Weight ]:
644.70

Related Compounds

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