2-(4-Benzylphenoxy)-N,N-diethylethylamine hydrochloride
Names
[ CAS No. ]:
92981-78-7
[ Name ]:
2-(4-Benzylphenoxy)-N,N-diethylethylamine hydrochloride
[Synonym ]:
Diaethyl-[2-(4-benzyl-phenoxy)-aethyl]-amin,Hydrochlorid
N,N-diethyl-2-[(4-phenylmethyl)phenoxy]ethanamine hydrochloride
Tesmilifene hydrochloride
N,N-diethyl-2-<4-(phenylmethyl)phenoxy>-ethaneamine * HCl
[2-(4-Benzoylbenzoyloxy)ethyl](dimethyl)[2-(myristoyloxy)-ethyl]ammoniumbromid
2-(4-benzoylbenzoyl)oxyethyl-dimethyl-(2-tetradecanoyloxyethyl)azanium bromide
Ethanaminium,2-((4-benzoylbenzoyl)oxy)-N,N-dimethyl-N-(2-((1-oxotetradecyl)oxy)ethyl)-,bromide
diethyl-[2-(4-benzyl-phenoxy)-ethyl]-amine,hydrochloride
[2-(4-benzylphenoxy)ethyl]diethylammonium chloride
Chemical & Physical Properties
[ Boiling Point ]:
397ºC at 760 mmHg
[ Molecular Formula ]:
C6H12N2NaO12P4Sm----
[ Molecular Weight ]:
603.97300
[ Flash Point ]:
116.8ºC
[ Exact Mass ]:
603.84600
[ PSA ]:
280.51000
[ LogP ]:
1.76460
MSDS
Safety Information
[ RIDADR ]:
UN 3077 9 / PGIII
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Articles
Eur. J. Cancer 33(1) , 122-8, (1997)
This study was designed to the elucidate sensitising effects of the intracellular histamine antagonist, N,N-diethyl-2[4-(phenylmethyl)phenoxy] ethanamine HCl (DPPE) on the antitumour activity of cis-d...
Effect of alpha-FMH and DPPE on colony-forming properties of human peripheral progenitor cells.Curr. Med. Chem. 9(14) , 1349-57, (2002)
Endogenous histamine regulates the haematopoiesis. Histidine decarboxylase inhibitor decreases the histamine level, and its intracellular antagonist decreases the histamine effect. The effect of histi...
Effects of tesmilifene, a substrate of CYP3A and an inhibitor of P-glycoprotein, on the pharmacokinetics of intravenous and oral docetaxel in rats.J. Pharm. Pharmacol. 62(8) , 1084-8, (2010)
It has been reported that docetaxel is a P-glycoprotein substrate and is metabolized via the cytochrome P450 (CYP) 3A subfamily in rats. Tesmilifene is a substrate of the CYP3A subfamily and is an inh...