5(8H)-Naphthacenone, 10-[[3-(3-cyano-4-morpholinyl)-2,3, 6-trideoxy-.alpha.-L-lyxo-hexopyranosyl]oxy]-7,9,10, 12-tetrahydro-6,8, 11-trihydroxy-8-(hydroxyacetyl)-12-imino-1-methoxy-, (8S-cis)-
Names
[ CAS No. ]:
92692-62-1
[ Name ]:
5(8H)-Naphthacenone, 10-[[3-(3-cyano-4-morpholinyl)-2,3, 6-trideoxy-.alpha.-L-lyxo-hexopyranosyl]oxy]-7,9,10, 12-tetrahydro-6,8, 11-trihydroxy-8-(hydroxyacetyl)-12-imino-1-methoxy-, (8S-cis)-
[Synonym ]:
3'-deamino-3'-(3-cyano-4-morpholinyl)-13-dihydrodaunorubicin
3'-deamino-3'-(3-cyano-4-morpholinyl)-5-iminodoxorubicin
3'-deamino-3'-(3-cyano-4-morpholinyl)-13-dihydrodoxorubicin
Chemical & Physical Properties
[ Density]:
1.56g/cm3
[ Boiling Point ]:
988ºC at 760mmHg
[ Molecular Formula ]:
C32H35N3O11
[ Molecular Weight ]:
637.63400
[ Flash Point ]:
551.3ºC
[ Exact Mass ]:
637.22700
[ PSA ]:
223.09000
[ LogP ]:
0.48978
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- QI9457580
- CHEMICAL NAME :
- 5(8H)-Naphthacenone, 7,9,10,12-tetrahydro-10-((3-(3-cyano-4-morpholinyl)-2 ,3,6-trideoxy-alpha-L -xylo-hexopyranosyl)oxy)-8-(hydroxyacetyl)-12-imino-1 -methoxy-6,8,11-trihy droxy-, (8S-cis)-
- CAS REGISTRY NUMBER :
- 92692-62-1
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C32-H35-N3-O11
- MOLECULAR WEIGHT :
- 637.70
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
- TYPE OF TEST :
- DNA damage
- TEST SYSTEM :
- Rodent - hamster Fibroblast
- DOSE/DURATION :
- 100 nmol/L
- REFERENCE :
- CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 49,5262,1989