NHE3-IN-2

Names

[ Name ]:
NHE3-IN-2

[Synonym ]:
MFCD02816999
Guanidine, N''-(6-chloro-4-phenyl-2-quinazolinyl)-
2-(6-Chloro-4-phenyl-2-quinazolinyl)guanidine
1-(6-chloro-4-phenylquinazolin-2-yl)guanidine

Biological Activity

[Description]:

NHE3-IN-2 is a Na+/H+ exchanger-3 (NHE3) inhibitor ( patent WO2001079186A1, example 6-Chlor-4-phenyl-2-chinazolinyl-guanidin)[1].

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> Sodium Channel

Research Areas >> Metabolic Disease

[References]

[1]. Rolf Gericke, et al. 2-guanidino-4-aryl-chinazoline als nhe-3-inhibitoren. WO2001079186A1.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
552.7±42.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₅H₁₂ClN₅

[ Molecular Weight ]:
297.74

[ Flash Point ]:
288.1±27.9 °C

[ Exact Mass ]:
297.078125

[ LogP ]:
2.67

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.725

Related Compounds

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