rac-cis-N-Desmethyl Sertraline Hydrochloride

[ Melting Point ]:
301-303ºC

[ Molecular Formula ]:
C₁₆H₁₆Cl₃N

[ Molecular Weight ]:
328.66400

[ Exact Mass ]:
327.03500

[ PSA ]:
26.02000

[ LogP ]:
6.42120

[ Symbol ]:

GHS02, GHS06, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H301 + H311 + H331-H370

[ Precautionary Statements ]:
P210-P260-P280-P301 + P310-P311

[ RIDADR ]:
UN1230 - class 3 - PG 2 - Methanol, solution

The pharmacokinetics of sertraline excretion into human breast milk: determinants of infant serum concentrations.

J. Clin. Psychiatry 64(1) , 73-80, (2003)

The purpose of this study was to attain a new landmark in the area of selective serotonin reuptake inhibitor therapy during lactation by establishing a basis for interpreting infant serum concentratio...

Novel N6-substituted adenosine 5'-N-methyluronamides with high selectivity for human adenosine A3 receptors reduce ischemic myocardial injury.

Am. J. Physiol. Heart Circ. Physiol. 285(6) , H2780-7, (2003)

We recently reported the identification of a novel human adenosine A3 receptor-selective agonist, (2S,3S,4R,5R)-3-amino-5-[6-[5-chloro-2-(3-methylisoxazol-5-ylmethoxy)benzylamino]purin-9-yl]-4-hydroxy...

Analysis of second-generation antidepressant drug, sertraline and its active metabolite, N-desmethyl sertraline in human plasma by a sensitive and selective liquid chromatography-tandem mass spectrometry method.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 877(3) , 221-9, (2009)

A precise, sensitive and high throughput liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for simultaneous determination of sertraline (SER) and its primary metabolite, N-desmethyl ser...

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