CARM1-IN-3

Names

[ Name ]:
CARM1-IN-3

Biological Activity

[Description]:

CARM1-IN-3 (compound 17b) is a potent and selective co-activator associated arginine methyltransferase (CARM1) inhibitor with IC50 values of 0.07, >25 µM for CARM1 and CARM3, respectively[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Epigenetics >> Histone Methyltransferase

[Target]

IC50: 0.07 µM (CARM1); >25 µM (CARM3)[1]

[References]

[1]. Wan H, et al. Benzo[d]imidazole inhibitors of Coactivator Associated Arginine Methyltransferase 1 (CARM1)--Hit to Lead studies. Bioorg Med Chem Lett. 2009 Sep 1;19(17):5063-6.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₄H₃₂N₄O₂

[ Molecular Weight ]:
408.54

Related Compounds

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