Wnt/β-catenin agonist 4

Names

[ CAS No. ]:
912784-79-3

[ Name ]:
Wnt/β-catenin agonist 4

Biological Activity

[Description]:

Wnt/β-catenin agonist 4 (Derivative 83) is an agonist of Wnt that activates Wnt/β-catenin signal transmission[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Stem Cell/Wnt >> Wnt

[Target]

Wnt[1]


[In Vitro]

Wnt/β-catenin agonist 4 (Derivative 83) (120 μM; 24 h) shows 1049% β-catenin activity in HEK293 and SW480 cells[1]. Wnt/β-catenin agonist 4 (11 μM; 4 days) shows 2848% ALP activity on differentiation of ST2 cell line into osteoblasts[1].

[References]

[1]. Jeong Woo Cho, et al. Isoxazole derivatives and use thereof. Patent WO2007078113A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C16H15FN4O2

[ Molecular Weight ]:
314.31

Related Compounds