Microsomal aminopeptidase

Names

[ Name ]:
Microsomal aminopeptidase

[Synonym ]:
MFCD00131501

Biological Activity

[Description]:

Microsomal aminopeptidase (microsomal aminoptidase) was first reported from C. elegans. The Microsomal aminopeptidase is beneficial for the development of molecular vaccines against parasitic nematodes[1].

[Related Catalog]:

Research Areas >> Metabolic Disease

[References]

[1]. Smith TS, et al. Cloning and characterization of a microsomal aminopeptidase from the intestine of the nematode Haemonchus contortus. Biochim Biophys Acta. 1997 Apr 4;1338(2):295-306.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₂H₂₄O₂

[ Molecular Weight ]:
200.31776

[ Appearance of Characters ]:
powder | white

[ Storage condition ]:
2-8°C

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
22-24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

Sodium solute symporter and cadherin proteins act as Bacillus thuringiensis Cry3Ba toxin functional receptors in Tribolium castaneum.

J. Biol. Chem. 288(25) , 18013-21, (2013)

Understanding how Bacillus thuringiensis (Bt) toxins interact with proteins in the midgut of susceptible coleopteran insects is crucial to fully explain the molecular bases of Bt specificity and insec...

Novel leucine ureido derivatives as inhibitors of aminopeptidase N (APN).

Bioorg. Med. Chem. 21(7) , 1621-7, (2013)

Aminopeptidase N (APN/CD13) over expressed on tumor cells, plays a critical role in tumor invasion, metastasis, and tumor angiogenesis. Here we described the design, synthesis and preliminary activity...

Synthesis and structure-activity relationships of phosphonic arginine mimetics as inhibitors of the M1 and M17 aminopeptidases from Plasmodium falciparum.

J. Med. Chem. 56(12) , 5213-7, (2013)

The malaria parasite Plasmodium falciparum employs two metallo-aminopeptidases, PfA-M1 and PfA-M17, which are essential for parasite survival. Compounds that inhibit the activity of either enzyme repr...

Related Compounds

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