USP10-IN-3
Names
[ CAS No. ]:
904448-58-4
[ Name ]:
USP10-IN-3
Biological Activity
[Description]:
USP10-IN-3 is a HBX19818 analog, potent and selective USP10 inhibitor, but does not inhibit USP7 (IC50>100 uM); demonstrates specificity for FLT3- mutant MOLM13-luc+, MOLM14 and MV4,11 cell lines relative to the FLT3-null TF-1 cell line and to other leukemia lines not driven by FLT3.
[References]
References 1. Weisberg EL, et al. Nat Chem Biol. 2017 Dec;13(12):1207-1215. View Related Products by Target Deubiquitinase (DUB)
Chemical & Physical Properties
[ Molecular Formula ]:
C23H32ClN3O
[ Molecular Weight ]:
401.979
Related Compounds
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