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N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)thio]-2-hydroxy-2-methylpropionamide

Names

[ CAS No. ]:
90356-78-8

[ Name ]:
N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)thio]-2-hydroxy-2-methylpropionamide

[Synonym ]:
4-Cyano-3-(trifluoromethyl)phenyl-3-(4-fluorophenyl)thio)-2-methylpropanamide
MFCD08063934
4-Cyano-3-trifluoromethyl-N-[3-(4-fluorophenylthio)-2-hydroxyl-2-methylpropionyl]aniline (Intermediate for Bicalutamide)
4-OYANO-3-TRIFLUOROMETHYL-N-[3-(4-FLUOROPHENYLTHIO)-2-HYDROXYL-2-METHYLPROPIONYL]ANILINE
N-(4-Cyano-3-trifluoromethyl-phenyl)-3-(4-fluoro-phenylsulfanyl)-2-hydroxy-2-methyl-propionamide
N-[4-CYANO-3-(TRIFLUOROMETHYL)PHENYL]-3-[(4-FLUOROPHENYL)THIO]-2-HYDROXY-2-MET
N-[4-Cyano-3-(Trifluoromethyl)Phenyl]-3-[(4-Fluorophenyl)thio]-2-Hydroxy-2-Methy
INTERMEDIATE OF BICALUTAMIDE
N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)thio]-2-hydroxy-2-methylpropanamide
4-cyano-3-trifluoromethyl-N-(3-p-fluorophenylthio-2-hydroxy-2-methylpropionyl)aniline
FXFFR BCN EMVXQ1&1SR DF
Bicalutamide Intermediate
BICALUTAMIDE-SULFIDE (BICALUTAMIDE ASH)
N-[4-Cyano-3-(trifluoromethyl)
4-CYANO-3-TRIFLUOROMETHYL-N-[3-(4-FLUOROPHENYLTHIO)-2-HYDROXYL-2-METHYLPROPIONYL]ANILINE
BicalutaMide Sulfide
N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfanyl]-2-hydroxy-2-methylpropanamide
Propanamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)thio]-2-hydroxy-2-methyl-

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
565.6±50.0 °C at 760 mmHg

[ Melting Point ]:
109-111°C

[ Molecular Formula ]:
C18H14F4N2O2S

[ Molecular Weight ]:
398.375

[ Flash Point ]:
295.9±30.1 °C

[ Exact Mass ]:
398.071198

[ PSA ]:
98.42000

[ LogP ]:
5.69

[ Vapour Pressure ]:
0.0±1.6 mmHg at 25°C

[ Index of Refraction ]:
1.585

[ Storage condition ]:
Refrigerator

Synthetic Route

Precursor & DownStream