Seneciphyllinine

Names

[ Name ]:
Seneciphyllinine

[Synonym ]:
(15Z)-11,16-Dioxo-13,19-didehydrosenecionan-12-yl acetate
[1,6]Dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione, 6-(acetyloxy)-3-ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-methyl-5-methylene-, (3Z,6R,14aR,14bR)-

Biological Activity

[Description]:

Seneciphyllinine, a pyrrolizidine alkaloid, is isolated from the roots of Gynura japonica. Pyrrolizidine alkaloids are highly hepatotoxic natural chemicals that produce irreversible chronic and acute hepatotoxic effects on human beings[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

[References]

[1]. Fang L, et al. Mass-spectrometry-directed analysis and purification of pyrrolizidine alkaloid cis/trans isomers in Gynura japonica. J Sep Sci. 2014 Aug;37(15):2032-8.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
585.3±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₀H₂₅NO₆

[ Molecular Weight ]:
375.416

[ Flash Point ]:
307.8±30.1 °C

[ Exact Mass ]:
375.168182

[ PSA ]:
82.14000

[ LogP ]:
1.72

[ Vapour Pressure ]:
0.0±1.6 mmHg at 25°C

[ Index of Refraction ]:
1.560

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds

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