Ovalbumins

Names

[ Name ]:
Ovalbumins

[Synonym ]:
Ovalbumins
protalbinicacid
MFCD00130424
HORSE ALBUMIN
egg
ALBUMIN, HORSE
Albuminegg,flake
crystalbumins
OVALBUMIN

Biological Activity

[Description]:

Ovalbumins, the main protein found in egg whites, have various biological activities such as anticancer, antihypertensive, antibacterial, antioxidant and immunomodulatory activities. Ovalbumins are the most abundant proteins synthesized in progesterone- or estrogen-treated fallopian tubes and are commonly used as markers to study hormone control of gene expression in this tissue[1].

[Related Catalog]:

Research Areas >> Cancer

Research Areas >> Inflammation/Immunology

[In Vivo]

Ovalbumins (OVA) (1 mg/kg, intranasal inoculation, 6 times over 2 weeks) (Silica nanoparticles)SNP/OVA 雌性 BALB/c 小鼠模型中，与 SNP 的联合给药会引起明显的气道过敏性炎症，导致总细胞、巨噬细胞、中性粒细胞增多，嗜酸性粒细胞、淋巴细胞增多[1]。

[References]

[1]. Heejae Han, et al. Toxic and adjuvant effects of silica nanoparticles on ovalbumin-induced allergic airway inflammation in mice. Respir Res. 2016 May 18;17(1):60.

Chemical & Physical Properties

[ Melting Point ]:
60°C

[ Storage condition ]:
2~8°C

Safety Information

[ Symbol ]:

GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H334

[ Precautionary Statements ]:
P261-P342 + P311

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
20/22-24-37/38-41-68

[ Safety Phrases ]:
53-26-36/37/39-45

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3.0

[ RTECS ]:
AY9384000

Articles

Inhibition of TRPM7 channels reduces degranulation and release of cytokines in rat bone marrow-derived mast cells.

Int. J. Mol. Sci. 15(7) , 11817-31, (2014)

mast cells play an important role in airway inflammation in asthma. The transient receptor potential melastatin-like 7 (TRPM7) channel is expressed in primary human lung mast cells and plays a critica...

Cytokine responses to egg protein in previously allergic children who developed tolerance naturally.

Ann. Allergy Asthma Immunol. 113(6) , 667-670.e4, (2014)

Lipopolysaccharides facilitate colonic motor alterations associated to the sensitization to a luminal antigen in rats.

J. Neurogastroenterol. Motil. 21(2) , 222-35, (2015)

Enteric dysbiosis is a risk factor for dietary proteins-associated intestinal alterations, contributing to the development of food allergies and the symptomatology of functional gastrointestinal disor...