Polyethyleneimine

Names

[ Name ]:
Polyethyleneimine

[Synonym ]:
MFCD00084427
Aziridine, homopolymer

Biological Activity

[Description]:

Polyethylenimine is a class of cationic polymers, is effective for gene delivery. Polyethylenimine is nondegradable and the molecular weight of PEI affects the cytotoxicity and gene transfer activity. Polyethylenimine acts as a low toxicity and efficient gene vector[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[References]

[1]. Yuting Wen, et al. A biodegradable low molecular weight polyethylenimine derivative as low toxicity and efficient gene vector. Bioconjug Chem. 2009 Feb;20(2):322-32.

Chemical & Physical Properties

[ Density]:
1.030 g/mL at 25 °C

[ Boiling Point ]:
250 °C(lit.)

[ Melting Point ]:
59-60°C

[ Molecular Formula ]:
C₂H₅N

[ Molecular Weight ]:
43.06780

[ Flash Point ]:
>230 °F

[ Exact Mass ]:
43.04220

[ PSA ]:
21.94000

[ Appearance of Characters ]:
Liquid | Pale yellow

[ Index of Refraction ]:
n20/D 1.5290

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
Soluble in water.

Safety Information

[ Symbol ]:

GHS07, GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H411

[ Precautionary Statements ]:
P273

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xn,N,Xi

[ Risk Phrases ]:
22-43-51/53-36/38

[ Safety Phrases ]:
22-24/25-61-36/37-37-26

[ RIDADR ]:
UN 3082 9 / PGIII

[ WGK Germany ]:
2

[ RTECS ]:
TQ7917000

[ Hazard Class ]:
9.0

Articles

Loss of INPP4B causes a DNA repair defect through loss of BRCA1, ATM and ATR and can be targeted with PARP inhibitor treatment.

Oncotarget 6 , 10548-62, (2015)

Treatment options for ovarian cancer patients remain limited and overall survival is less than 50% despite recent clinical advances. The lipid phosphatase inositol polyphosphate 4-phosphatase type II ...

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.