APL (hormone)

Names

[ Name ]:
APL (hormone)

[Synonym ]:
EINECS 232-660-2
MFCD00130797
HCG

Biological Activity

[Description]:

APL (hormone) (Ambinon) is a gonadotropin that can be isolated from the anterior pituitary gland. APL (hormone) has potential applications in ovarian and follicular development[1].

[Related Catalog]:

Research Areas >> Endocrinology

[In Vivo]

APL (hormone) (0.5 mL/d；肌肉注射；6 d) 导致母鸡卵泡发生退化，卵巢受损[1]。 APL (hormone) (0.25 mL/d；肌肉注射；9 d) 在小雏鸡中显著促进了卵巢的增重[1]。 APL (hormone) (0.5 mL/d；肌肉注射；9 d) 导致小雏鸡的卵泡出现退化的迹象[1]。 APL (hormone) (0.2 mL/d；1、2、3、4、5、6 和 7 weeks) 对接受垂体切除术的大鼠的体重、尾部长度和眼睛屈光度无显著影响[2]。 Animal Model: White Leghorn, Barred Plymouth Rock, and Barred Plymouth Rock X New Hampshire crossbred hens and pullets[1]. Dosage: 0.25 mL/d and 0.5 mL/d. Administration: Intramuscular injection; 6 d and 9 d. Result: Hindered the normal development of the ovaries and follicles.

[References]

[1]. Phillips R E. Ovarian response of hens and pullets to injections of Ambinon[J]. Poultry Science, 1943, 22(5): 368-373.

[2]. Alphen CC, et al. Endocrine influences on the refraction of the eyes of young rats. Ophthalmologica. 1976;173(3-4):328-32.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₇H₂₈

[ Molecular Weight ]:
232.40422

[ Appearance of Characters ]:
lyophilized powder

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
H2O: soluble1ML/vial

Safety Information

[ Symbol ]:

GHS08

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H361

[ Precautionary Statements ]:
P280

[ Hazard Codes ]:
B,Xn

[ Risk Phrases ]:
63-62

[ Safety Phrases ]:
22-36-36/37

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
MD6953000

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[Comparison of the amounts of hCG and PMSG to induce ovulation in 50% of the animals, mice, Syrian hamsters and rats].

Jikken Dobutsu. 41(2) , 153-9, (1992)

On the day of diestrus, female mice, syrian hamsters and rats, showing regular 4-day estrous cycles, were injected with hCG or PMSG and were inspected for the presence of ovulation the following day. ...

Related Compounds

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