Pepsin

Names

[ Name ]:
Pepsin

[Synonym ]:
MFCD00081840
EINECS 232-629-3

Biological Activity

[Description]:

Pepsin A is the major pig and human gastric proteases, it is a pepsin-like minor gastric proteolytic enzymes. Pepsin A contributes to proteolysis of food proteins in the vertebrate stomach[1][2].

[Related Catalog]:

Research Areas >> Endocrinology

[References]

[1]. K.Yamamoto, et al. Cathepsin E: An Aspartic Protease with Diverse Functions and Biomedical Implications. Encyclopedia of Cell Biology. 2016.

[2]. Jordan Tang. Chapter 3 - Pepsin A. Handbook of Proteolytic Enzymes. 2013.

Chemical & Physical Properties

[ Molecular Formula ]:
n_.a_.

Safety Information

[ Symbol ]:

GHS07, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H315-H319-H334-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338-P342 + P311

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
R36/37/38;R42

[ Safety Phrases ]:
S22;S24;S26;S36/37

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
1

[ RTECS ]:
SC6132000

Articles

Curcumin and anthocyanin inhibit pepsin-mediated cell damage and carcinogenic changes in airway epithelial cells.

Ann. Otol. Rhinol. Laryngol. 122(10) , 632-41, (2013)

Laryngopharyngeal reflux (LPR) is associated with inflammatory and neoplastic airway diseases. Gastric pepsin internalized by airway epithelial cells during reflux contributes to oxidative stress, inf...

A synchrotron-based hydroxyl radical footprinting analysis of amyloid fibrils and prefibrillar intermediates with residue-specific resolution.

Biochemistry 53(49) , 7724-34, (2014)

Structural models of the fibrils formed by the 40-residue amyloid-β (Aβ40) peptide in Alzheimer's disease typically consist of linear polypeptide segments, oriented approximately perpendicular to the ...

Changes in the Factor VIII C2 domain upon membrane binding determined by hydrogen-deuterium exchange MS.

Biochem. J. 461(3) , 443-51, (2014)

Factor VIII enhances the catalytic activity of Factor IXa in a membrane-bound enzyme complex and both proteins are necessary to prevent haemophilia. Tandem lectin-like C domains mediate the membrane b...

Related Compounds

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