STING-IN-7

Names

[ Name ]:
STING-IN-7

Biological Activity

[Description]:

STING-IN-7 (compound 21) is a potent STING inhibitor with an IC50 of 11.5 nM. STING-IN-7 inhibits the phosphorylation of STING and interferon regulatory factor 3 (IRF3)[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Immunology/Inflammation >> STING

[References]

[1]. Po-Wei Chang, et al. Analysis of structure-activity relationship of indol-3-yl-N-phenylcarbamic amides as potent STING inhibitors. Bioorg Med Chem. 2023 Oct 14:95:117502.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₆H₁₄ClN₃O

[ Molecular Weight ]:
299.75

Related Compounds

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