Cabenoside D

Names

[ Name ]:
Cabenoside D

Biological Activity

[Description]:

Cabenoside D (compound 8) is a triterpenoid glycoside, which can be isolated from the methanol extract of lichen root. Cabenoside D shows anti-inflammatory activity and inhibits inflammation induced by 12-O-tetracylacyl hormone-13-acetate (TPA) in mice. Cabenoside D also inhibits TPA-induced Epstein-Barr virus (EBV) early antigen (EBV-EA) activation[1].

[Related Catalog]:

Research Areas >> Infection

Research Areas >> Inflammation/Immunology

[In Vitro]

Cabenoside D (化合物 8) (10-1000 mol ratio/TPA, TPA=32 pmol, 20 ng) 呈浓度依赖效应地抑制 TPA 诱导的 Epstein-Barr 病毒 (EBV) 早期抗原 (EBV-EA) 激活[1]。

[In Vivo]

Cabenoside D (化合物 8) (0.6 mg/ear; single dose) 对 TPA 诱导的小鼠炎症有抑制作用，抑制率达到 66%[1]。

[References]

[1]. Ukiya M, et al. Anti-inflammatory and anti-tumor-promoting effects of cucurbitane glycosides from the roots of Bryonia dioica. J Nat Prod. 2002 Feb;65(2):179-83.

[2]. Ukiya M, et al. Anti-inflammatory and anti-tumor-promoting effects of cucurbitane glycosides from the roots of Bryonia dioica. J Nat Prod. 2002 Feb;65(2):179-83.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₆H₆₀O₉

[ Molecular Weight ]:
636.86

Related Compounds

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