Bafetinib

Names

[ Name ]:
Bafetinib

[Synonym ]:
Benzamide, N-[3-([5,5'-bipyrimidin]-2-ylamino)-4-methylphenyl]-4-[[(3S)-3-(dimethylamino)-1-pyrrolidinyl]methyl]-3-(trifluoromethyl)-
N-[3-(5,5'-Bipyrimidin-2-ylamino)-4-methylphenyl]-4-{[(3S)-3-(dimethylamino)-1-pyrrolidinyl]methyl}-3-(trifluoromethyl)benzamide
QCR-131
cc-271
INNO-406,NS-187,Bafetinib
S1369_Selleck
Lyn-IN-1

Biological Activity

[Description]:

Lyn-IN-1 is a potent and selective dual Bcr-Abl/Lyn inhibitor, extracted from patent WO2014169128A1.

[Related Catalog]:

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Bcr-Abl

Research Areas >> Cancer

[References]

[1]. From PCT Int.Appl.(2014), WO2014169128A1

[Related Small Molecules]

Nocodazole | Asciminib | Degrasyn(WP1130) | Bafetinib (INNO-406) | DCC-2036 (Rebastinib) | KW-2449 | AST 487 | PD173955 | XL228 | DPH | GNF-2 | GNF-7 | GZD824 | Flumatinib | GNF-5

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Molecular Formula ]:
C₃₀H₃₁F₃N₈O

[ Molecular Weight ]:
576.615

[ Exact Mass ]:
576.257263

[ PSA ]:
99.17000

[ LogP ]:
3.03

[ Index of Refraction ]:
1.640

Related Compounds

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