11,12-Dihydroxyabieta-8(14),9(11),12-trien-7-one

Names

[ Name ]:
11,12-Dihydroxyabieta-8(14),9(11),12-trien-7-one

[Synonym ]:
9(1H)-Phenanthrenone, 2,3,4,4a,10,10a-hexahydro-5,6-dihydroxy-1,1,4a-trimethyl-7-(1-methylethyl)-, (4aS,10aS)-
12-O-DEMETHYLCRYPTOJAPANOL
11,12-Dihydroxyabieta-8(14),9(11),12-trien-7-one
11-Hydroxysugiol
11-hydroxy-sugiol

Biological Activity

[Description]:

11-Hydroxysugiol regulates the SUMOylation of intracellular receptors by modulating RARα and vitamin D3 receptor (VDR)[1].

[Related Catalog]:

Signaling Pathways >> Vitamin D Related >> VD/VDR

Research Areas >> Infection

Signaling Pathways >> Metabolic Enzyme/Protease >> RAR/RXR

[Target]

RARα

[References]

[1]. Meenaxi M. Maste, et al. Screening of Plectranthus amboinicus against COVID-19-in silico approach. J App Pharm Sci. 2020; 10(12): 90-97.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
482.2±45.0 °C at 760 mmHg

[ Melting Point ]:
192-194 °C

[ Molecular Formula ]:
C₂₀H₂₈O₃

[ Molecular Weight ]:
316.43

[ Flash Point ]:
259.5±25.2 °C

[ Exact Mass ]:
316.203857

[ PSA ]:
57.53000

[ LogP ]:
6.63

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.556

Safety Information

[ Hazard Codes ]:
Xi

Precursor & DownStream

Precursor

DownStream

Related Compounds

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