Boc-NH-PEG6-CH2CH2COOH

Names

[ Name ]:
Boc-NH-PEG6-CH2CH2COOH

[Synonym ]:
21-(Boc-aMino)-4,7,10,13,16,19-hexaoxaheneicosanoic acid
Boc-21-amino-4,7,10,13,16,19-hexaoxaheneicosanoic acid
Boc-N-amido-PEG6-acid
Boc-NH-PEG6-CH2CH2COOH
5,8,11,14,17,20-Hexaoxa-2-azatricosanedioic acid 1-(1,1-dimethylethyl) ester

Biological Activity

[Description]:

Boc-NH-PEG6-CH2CH2COOH is a cleavable ADC linker used as a linker for antibody-drug conjugates (ADC)[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Cleavable

[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

[References]

[1]. Michael J. Mcpherson, et al. Glucocorticoid receptor agonist and immunoconjugates thereof. WO2017210471A1.

Chemical & Physical Properties

[ Density]:
1.123±0.06 g/cm3

[ Molecular Formula ]:
C₂₀H₃₉NO₁₀

[ Molecular Weight ]:
453.52400

[ Exact Mass ]:
453.25700

[ PSA ]:
131.01000

[ LogP ]:
1.47630

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
Freely soluble (150 g/L) (25 ºC)

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
29225090

Related Compounds

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