<Suppliers Price>

MB-07729

Names

[ CAS No. ]:
882755-95-5

[ Name ]:
MB-07729

[Synonym ]:
{5-[2-amino-5-(2,2-dimethylpropionyl)thiazol-4-yl]furan-2-yl}phosphonic acid
{5-[2-amino-5-(2,2-dimethylpropionyl)thiazol-4-yl]-furan-2-yl}phosphonic acid

Biological Activity

[Description]:

MB-07729 is a potent fructose 1,6-bisphosphatase (FBPase) noncompetitive inhibitor with IC50 values of 31, 121, and 189 nM for human, monkey, and rat, respectively.

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Metabolic Disease

[Target]

31, 121, and 189 nM for human, monkey, and rat, respectively [1] .


[References]

[1]. PAUL D. VAN POELJE，et al. MB07803, a Prodrug of a Second Generation Fructose-1,6-Bisphosphatase Inhibitor, Lowers Blood Glucose in Diabetic Rodents and in Cynomolgus Monkeys.


[Related Small Molecules]

Captisol | Cyclosporin A | H2DCFDA | 0MPTP hydrochloride | GW4869 | Etomoxir | TD139 | Mitoquinone mesylate | GSK2795039 | JC-1 | BAPTA-AM | AP 20187 | Setanaxib (GKT137831) | D-Luciferin | Crotaline

Chemical & Physical Properties

[ Molecular Formula ]:
C12H15N2O5PS

[ Molecular Weight ]:
330.29700

[ Exact Mass ]:
330.04400

[ PSA ]:
164.70000

[ LogP ]:
2.59830

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.