Anhydro notoptol

Names

[ Name ]:
Anhydro notoptol

[Synonym ]:
4-((2E,5E)-3,7-Dimethyl-octa-2,5,7-trienyloxy)-furo[3,2-g]chromen-7-one

Biological Activity

[Description]:

Anhydronotoptol is a potent nitric oxide inhibitory coumarin. Anhydronotoptol inhibits NO production in RAW 264.7 cells induced by LPS with an IC50 value of 36.6 μM[1].

[Related Catalog]:

Signaling Pathways >> Immunology/Inflammation >> NO Synthase

Research Areas >> Inflammation/Immunology

[References]

[1]. Xikang Zheng, et al. Nitric oxide inhibitory coumarins from the roots and rhizomes of Notopterygium incisum. Fitoterapia. 2018 Nov;131:65-72.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₁H₂₀O₄

[ Molecular Weight ]:
336.38

[ Exact Mass ]:
336.13600

[ PSA ]:
52.58000

[ LogP ]:
5.38670

Related Compounds

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